The major focus of the research undertaken in the Thurecht Group is biologically driven nanomaterial design. To achieve this goal, the research topics we investigate attempt to answer these main questions:
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Can the contribution of targeting cellular proteins be assessed directly, and what affect does it have on the accumulation of nanomedicines.
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How do nanoparticles interact with the tumour microenvironment?
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Can molecular imaging be used as a tool to validate the efficacy of nanotherapeutics?
To answer these questions, the research in the Thurecht Group is divided into the following categories. Click on the button for each category to see the research projects and people involved to answer these questions.
TheranosticsNovel nanomaterials with both a diagnostic and therapeutic component have allowed for more efficient therapies and a deeper understanding of their biological interactions and affect on disease.
Smart NanomedicinesThe shape, size, and physical characteristics of the nanomedicine are crucial to effective function. We are continually developing new materials in order to study their biological behavior in the body and in the cell.
Molecular ImagingThe complexity of diseases require more sophisticated and responsive imaging probes for the areas of MRI, PET, and optical imaging techniques. By creating novel materials that navigate the body efficiently and respond to disease specific stimuli and markers, we are continuing to develop better imaging probes to enhance disease diagnosis.
Cellular InteractionsTreatment of disease happens on a cellular level. We are actively investigating how our nanomaterials localise and internalise inside the target cell.
