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20 January
0

Biological interactions of polymers for nanomedicine and molecular imaging

Arunpandian Balaji   |   Cellular Response to Nanomedicine, Nanomedicines and Smart Materials, Theranostics   |   No comment

[vc_row row_type="row" text_align="left" css_animation=""][vc_column width="2/3"][vc_column_text] In terms of developing nanomedicines with clinical translation in mind: what makes some polymer designs perform better in vivo than others? Why do some materials demonstrate a higher susceptibility to falling prey to biological barriers than others do? As designs for nanomedical delivery vectors...

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17 January
0

Targeted stealth nanoparticles: Design, synthesis and understanding it’s in vivo response by balancing the stealth versus targeting components

Arunpandian Balaji   |   Cellular Response to Nanomedicine, Nanomedicines and Smart Materials, Theranostics   |   No comment

[vc_row row_type="row" text_align="left" css_animation=""][vc_column width="2/3"][vc_column_text] Targeted nanomedicines have significantly changed the way new therapeutics are designed to treat disease.1 The ability to integrate nanomaterials with biological components has led to the development of new generation devices, diagnostic tools and biotechnology-derived therapeutic-enhancing products. While such conjugates show...

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17 January
0

Developing bioorthogonal smart polymers for cancer therapy

Arunpandian Balaji   |   In Vivo Molecular Imaging, Nanomedicines and Smart Materials, Theranostics   |   No comment

[vc_row row_type="row" text_align="left" css_animation=""][vc_column width="2/3"][vc_column_text] The selective delivery and effective localisation of drugs is crucial in cancer therapy. Conventional chemotherapy is subjected to certain drawbacks, such as limitation of tumour-specific receptors that ensure efficient internalisation to enhance drug release as well as significant systemic toxicity to...

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17 January
0

Development of novel polymeric theranostic for the treatment of colorectal cancer

Arunpandian Balaji   |   Cellular Response to Nanomedicine, Nanomedicines and Smart Materials, Theranostics   |   No comment

[vc_row row_type="row" text_align="left" css_animation=""][vc_column width="2/3"][vc_column_text] Off targeted delivery of chemotherapeutics is a major barrier for successful anticancer drug therapies by intravenous administration. The primary aim of this project is to develop suitable oral drug delivery systems for the effective treatment of colorectal cancer. Polymeric micelles was...

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17 January
0

Novel polymeric materials that show responsive behaviour within tissue

Arunpandian Balaji   |   In Vivo Molecular Imaging, Nanomedicines and Smart Materials, Theranostics   |   No comment

[vc_row row_type="row" text_align="left" css_animation=""][vc_column width="2/3"][vc_column_text] There remains a large number of unknowns surrounding how nanomedicines interact with the heterogeneous tumour microenvironment and how certain particles permeate through the tumour mass. Here we aim to gain insight into the nanoparticle-tumour interaction by means of photoacoustic (PA) molecular...

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17 January
0

Self-assembled polymeric theranostics for hepatic fibrosis – an approach to non-invasive staging and targeted drug delivery

Arunpandian Balaji   |   In Vivo Molecular Imaging, Theranostics   |   No comment

[vc_row row_type="row" text_align="left" css_animation="" css=".vc_custom_1547786106869{background-image: url(http://thurecht.cai.uq.edu.au/wp-content/uploads/2019/01/Minomic_M157_48h_VR_forweb.png?id=9696) !important;}"][vc_column css=".vc_custom_1547773147138{background-color: rgba(255,255,255,0.5) !important;*background-color: rgb(255,255,255) !important;}"][vc_empty_space height="128px"][vc_row_inner row_type="row" text_align="left" css_animation=""][vc_column_inner width="2/3"][vc_custom_heading text="Self-assembled polymeric theranostics for hepatic fibrosis - an approach to non-invasive staging and targeted drug delivery" font_container="tag:h2|font_size:26|text_align:center|color:%23000000" google_fonts="font_family:Bitter%3Aregular%2Citalic%2C700|font_style:700%20bold%20regular%3A700%3Anormal"][vc_empty_space][vc_column_text] Hepatic fibrosis (HF) is a common pathological feature of different liver...

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